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Welcome to the FastFacts area of the New Insights into HE educational resource.

One of the most important causes of cognitive dysfunction in patients with cirrhosis is hepatic encephalopathy (HE).1

This FastFacts area includes a number of resources to help you identify patients with HE and initiate appropriate management. HE is associated with substantial morbidity and significant mortality.2 The need for better identification and management of patients with HE is explored by our faculty in the educational programme.

This website is appropriate for both those with a primary interest in liver disease and those with more diverse clinical responsibilities.

FastFacts modules

  • Epidemiology and burden of HE

  • Pathophysiology and diagnosis of HE

  • Treatment of HE

  • Interactive case scenario

Instructions for use
There are four ‘FastFacts’ modules which you can access in any order. Each module will take approximately 5-10 minutes to complete. You can track which modules you have viewed by the indicator buttons next to each module. In order to obtain a FastFacts certificate of completion, you will need to complete the Post-activity test and Evaluation.

Please access the Post-activity test here.

For more in-depth educational information and resources please access the main site

‘How I...’ diagnostic videos

make a diagnosis

A clinically focused series of 'tips' on the differential clinical diagnosis of HE

do pencil and paper tests

A practical guide on how to administer and interpret commonly used pencil and paper tests of cognitive function

use and interpret an EEG

A practical guide on the interpretation of EEG results in the context of HE

perform and use an EEG

When to consider ordering an EEG for your patients, what to ask for, how to perform an EEG and interpret the results

Some individuals pictured are models and are used for illustrative purposes only

FastFacts Faculty

This programme has been developed under the direction of the New Insights into HE Faculty. Please see the New Insights into HE main site for further details of the Steering Committee.
Professor Rajiv Jalan (Course Director)
Royal Free Hospital/UCL Medical School, London, UK
Professor Wim Laleman University Hospital Gasthuisberg, Leuven, Belgium
Dr. Arthur Dunk
Eastbourne District General Hospital, East Sussex, UK
Dr. John Ramage
Hampshire Hospitals NHS Foundation Trust, Basingstoke, Hants, UK


Dr. Sara Montagnese
Department of Medicine, University of Padova, Italy
Dr. Debbie Shawcross
King's College Hospital/King's College, London School of Medicine, London, UK

Editorial Assistance

Content development was supported by Ian Morgan MSc and Helen Jones PhD, Strategic Consultants International

The development of these activities was
co-ordinated by Strategic Consultants International

Date of preparation August 2018. 1. Bajaj J S. Aliment Pharmacol Ther 2010; 31: 537-547. 2. Cordoba J, et al. J Hepatol 2014; 60: 275-281.